Endocrine Abstracts

Introduction: Graves’ hyperthyroidism affects 0.2–2% of women and 1–5% of infants born to these mothers will be symptomatic. Neonatal thyrotoxicosis is a potentially life-threatening condition and infants are currently monitored in hospital till day 4 of life. Graves’ disease is caused by TSH-receptor antibodies (TRAb) which can cross from the maternal to the foetal circulation where they may stimulate the developing thyroid gland causing neonatal thyrotoxi...